| Rank | City | 2006 Population (Est.) |
|---|---|---|
| 501 | Harlingen, TX | 61,823 |
| 502 | Springdale, AR | 61,800 |
| 503 | Lafayette, IN | 61,783 |
| 504 | Layton, UT | 61,753 |
| 505 | Huntington Park, CA | 61,650 |
| 506 | Edinburg, TX | 61,519 |
| 507 | Hamilton, OH | 61,495 |
| 508 | Lodi, CA | 61,484 |
| 509 | Pittsburg, CA | 61,425 |
| 510 | Johns Creek, GA | 61,385 |
| 511 | Victoria, TX | 61,289 |
| 512 | Schenectady, NY | 61,230 |
| 513 | Monterey Park, CA | 61,215 |
| 514 | St. Clair Shores, MI | 61,110 |
| 515 | Davis, CA | 60,981 |
| 516 | Camarillo, CA | 60,923 |
| 517 | Palm Coast, FL | 60,895 |
| 518 | Bristol, CT | 60,869 |
| 519 | North Richland Hills, TX | 60,864 |
| 520 | League City, TX | 60,657 |
| 521 | Eden Prairie, MN | 60,412 |
| 522 | Waltham, MA | 60,383 |
| 523 | Bossier City, LA | 60,119 |
| 524 | Concord, NC | 60,095 |
| 525 | South San Francisco, CA | 60,084 |
| 526 | Loveland, CO | 60,067 |
| 527 | Haverhill, MA | 59,926 |
| 528 | Jonesboro, AR | 59,807 |
| 529 | West Allis, WI | 59,790 |
| 530 | Tamarac, FL | 59,593 |
| 531 | San Clemente, CA | 59,523 |
| 532 | Maple Grove, MN | 59,465 |
| 533 | Council Bluffs, IA | 59,453 |
| 534 | North Little Rock, AR | 59,445 |
| 535 | Mount Pleasant, SC | 59,357 |
| 536 | Kissimmee, FL | 59,344 |
| 537 | Mission, TX | 59,337 |
| 538 | Bayonne, NJ | 59,306 |
| 539 | Rock Hill, SC | 59,285 |
| 540 | Encinitas, CA | 59,261 |
| 541 | La Habra, CA | 59,125 |
| 542 | Meriden, CT | 59,043 |
| 543 | Johnson City, TN | 58,974 |
| 544 | Gardena, CA | 58,864 |
| 545 | Utica, NY | 58,722 |
| 546 | Burnsville, MN | 58,707 |
| 547 | Auburn, WA | 58,610 |
| 548 | Rocky Mount, NC | 58,535 |
| 549 | North Miami, FL | 58,321 |
| 550 | Great Falls, MT | 58,280 |
| 551 | Yuba City, CA | 58,232 |
| 552 | Terre Haute, IN | 58,212 |
| 553 | Pharr, TX | 57,926 |
| 554 | Bismarck, ND | 57,818 |
| 555 | Gaithersburg, MD | 57,803 |
| 556 | Royal Oak, MI | 57,774 |
| 557 | Saginaw, MI | 57,761 |
| 558 | Fort Myers, FL | 57,723 |
| 559 | Vineland, NJ | 57,695 |
| 560 | Flagstaff, AZ | 57,681 |
| 561 | Warner Robins, GA | 57,665 |
| 562 | Frederick, MD | 57,623 |
| 563 | Taylorsville, UT | 57,538 |
| 564 | Shawnee, KS | 57,478 |
| 565 | Rockville, MD | 57,473 |
| 566 | Tinley Park, IL | 57,395 |
| 567 | Temple, TX | 57,362 |
| 568 | Dubuque, IA | 57,252 |
| 569 | White Plains, NY | 57,250 |
| 570 | Renton, WA | 57,234 |
| 571 | Anderson, IN | 57,194 |
| 572 | Galveston, TX | 57,194 |
| 573 | Fishers, IN | 57,182 |
| 574 | Diamond Bar, CA | 57,182 |
| 575 | Lakewood, WA | 57,148 |
| 576 | Greenville, SC | 57,144 |
| 577 | Palo Alto, CA | 56,406 |
| 578 | Des Plaines, IL | 56,206 |
| 579 | Port Arthur, TX | 56,199 |
| 580 | Rancho Cordova, CA | 55,924 |
| 581 | Taunton, MA | 55,841 |
| 582 | Chicopee, MA | 55,826 |
| 583 | Springfield, OR | 55,799 |
| 584 | Medford, MA | 55,798 |
| 585 | Paramount, CA | 55,765 |
| 586 | Dearborn Heights, MI | 55,761 |
| 587 | Malden, MA | 55,748 |
| 588 | Carson City, NV | 55,731 |
| 589 | Elyria, OH | 55,718 |
| 590 | Margate, FL | 55,646 |
| 591 | Cheyenne, WY | 55,392 |
| 592 | Arcadia, CA | 55,370 |
| 593 | Fountain Valley, CA | 55,338 |
| 594 | Lancaster, PA | 55,236 |
| 595 | Kettering, OH | 55,211 |
| 596 | Midwest City, OK | 55,185 |
| 597 | Owensboro, KY | 55,146 |
| 598 | San Rafael, CA | 55,071 |
| 599 | Pensacola, FL | 55,015 |
| 600 | Orland Park, IL | 54,914 |
Cities in Bold = State Capitals
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