| Rank | City | 2006 Population (Est.) | Growth Rate (Annual) |
|---|---|---|---|
| 1 | Charlotte | 631,160 | 2.1% |
| 2 | Raleigh | 347,681 | 3.7% |
| 3 | Greensboro | 236,449 | 0.7% |
| 4 | Winston-Salem | 216,961 | 1.4% |
| 5 | Durham | 205,613 | 1.7% |
| 6 | Fayetteville | 193,639 | -0.6% |
| 7 | Cary | 107,353 | 2.0% |
| 8 | Wilmington | 96,953 | 1.6% |
| 9 | High Point | 95,245 | 1.9% |
| 10 | Asheville | 73,392 | 0.1% |
| 11 | Jacksonville | 72,923 | 2.1% |
| 12 | Greenville | 70,328 | 2.3% |
| 13 | Gastonia | 68,230 | 0.2% |
| 14 | Concord | 60,095 | 1.2% |
| 15 | Rocky Mount | 58,535 | -0.1% |
| 16 | Chapel Hill | 49,925 | 0.8% |
| 17 | Burlington | 47,188 | 0.5% |
| 18 | Wilson | 46,553 | 0.7% |
| 19 | Hickory | 39,812 | 1.1% |
| 20 | Kannapolis | 38,966 | 0.8% |
| 21 | Goldsboro | 38,921 | -0.6% |
| 22 | Huntersville | 36,368 | 6.8% |
| 23 | Salisbury | 30,059 | -0.3% |
| 24 | Monroe | 29,583 | 1.6% |
| 25 | Apex | 28,994 | 6.4% |
| 26 | Sanford | 26,648 | 2.6% |
| 27 | New Bern | 26,468 | 2.6% |
| 28 | Thomasville | 25,535 | 0.8% |
| 29 | Matthews | 25,156 | 1.7% |
| 30 | Statesville | 24,780 | 1.0% |
| 31 | Asheboro | 23,416 | 1.1% |
| 32 | Garner | 22,941 | 4.0% |
| 33 | Kinston | 22,546 | -1.1% |
| 34 | Havelock | 22,343 | -0.1% |
| 35 | Lumberton | 21,237 | 0.1% |
| 36 | Kernersville | 21,070 | 2.3% |
| 37 | Shelby | 21,051 | 0.2% |
| 38 | Mooresville | 20,504 | 1.0% |
| 39 | Cornelius | 20,291 | 7.4% |
| 40 | Lexington | 20,091 | 0.2% |
| 41 | Wake Forest | 20,016 | 8.9% |
| 42 | Elizabeth City | 18,476 | 1.4% |
| 43 | Mint Hill | 18,197 | 1.0% |
| 44 | Lenoir | 17,811 | -0.4% |
| 45 | Carrboro | 17,388 | -0.4% |
| 46 | Morganton | 16,938 | -0.6% |
| 47 | Roanoke Rapids | 16,299 | -0.8% |
| 48 | Indian Trail | 16,151 | 3.5% |
| 49 | Clemmons | 16,051 | 0.3% |
| 50 | Henderson | 15,800 | -0.7% |
| 51 | Laurinburg | 15,476 | -0.6% |
| 52 | Eden | 15,452 | -0.5% |
| 53 | Albemarle | 15,435 | -0.7% |
| 54 | Holly Springs | 15,389 | 8.7% |
| 55 | Reidsville | 14,702 | 0.1% |
| 56 | Graham | 13,865 | 0.9% |
| 57 | Boone | 13,463 | -0.1% |
| 58 | Hope Mills | 13,300 | 1.8% |
| 59 | Newton | 12,995 | 0.4% |
| 60 | Clayton | 12,793 | 8.3% |
| 61 | Spring Lake | 12,704 | 0.3% |
| 62 | Fuquay-Varina | 12,381 | 8.6% |
| 63 | Morrisville | 12,184 | 17.0% |
| 64 | Smithfield | 11,932 | 1.6% |
| 65 | Lewisville | 11,879 | 0.3% |
| 66 | Southern Pines | 11,765 | 1.2% |
| 67 | Hendersonville | 11,655 | 0.4% |
| 68 | Pinehurst | 11,257 | 2.8% |
| 69 | Kings Mountain | 10,677 | 0.7% |
| 70 | Mount Airy | 10,649 | -0.4% |
| 71 | Tarboro | 10,437 | -1.4% |
| 72 | Lincolnton | 10,221 | 0.2% |
| 73 | Washington | 9,776 | 0.1% |
| 74 | Dunn | 9,730 | 0.9% |
| 75 | Mount Holly | 9,622 | -0.1% |
| 76 | Waynesville | 9,555 | -0.1% |
| 77 | Archdale | 9,090 | -0.0% |
| 78 | Mebane | 8,961 | 3.2% |
| 79 | Rockingham | 8,914 | -1.4% |
| 80 | Belmont | 8,904 | 0.0% |
| 81 | Morehead City | 8,856 | 2.3% |
| 82 | Davidson | 8,832 | 4.0% |
| 83 | Roxboro | 8,690 | -0.0% |
| 84 | Clinton | 8,605 | -0.0% |
| 85 | Oxford | 8,418 | 0.0% |
| 86 | Weddington | 8,293 | 4.1% |
| 87 | Siler City | 8,075 | 2.6% |
| 88 | Stallings | 7,742 | 1.4% |
| 89 | Black Mountain | 7,703 | 0.4% |
| 90 | Oak Island | 7,600 | 2.7% |
| 91 | Summerfield | 7,231 | 1.0% |
| 92 | Forest City | 7,121 | -1.1% |
| 93 | Elon | 7,070 | 0.7% |
| 94 | Conover | 7,028 | 0.8% |
| 95 | Marion | 6,879 | 0.0% |
| 96 | Trinity | 6,809 | 0.3% |
| 97 | Brevard | 6,645 | -0.5% |
| 98 | Knightdale | 6,623 | 1.0% |
| 99 | Selma | 6,576 | 1.5% |
| 100 | Kill Devil Hills | 6,491 | 1.9% |
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