| Rank | City | 2022 Population (Est.) | Growth Rate (Annual) | 
|---|---|---|---|
| 1 | Jackson | 149,761 | -2.0% | 
| 2 | Gulfport | 72,105 | -1.0% | 
| 3 | Southaven | 55,429 | 1.2% | 
| 4 | Biloxi | 49,241 | -0.4% | 
| 5 | Hattiesburg | 47,068 | -0.4% | 
| 6 | Olive Branch | 40,276 | 0.9% | 
| 7 | Tupelo | 37,667 | -0.4% | 
| 8 | Meridian | 34,424 | -1.2% | 
| 9 | Greenville | 28,777 | -2.3% | 
| 10 | Madison | 27,719 | -0.2% | 
| 11 | Clinton | 27,451 | -1.6% | 
| 12 | Pearl | 27,258 | 0.8% | 
| 13 | Horn Lake | 26,737 | -0.0% | 
| 14 | Oxford | 26,430 | 2.1% | 
| 15 | Brandon | 25,373 | 1.0% | 
| 16 | Starkville | 24,657 | 0.3% | 
| 17 | Ridgeland | 24,058 | -0.7% | 
| 18 | Columbus | 23,319 | -1.5% | 
| 19 | Pascagoula | 21,849 | -0.5% | 
| 20 | Vicksburg | 20,904 | -2.5% | 
| 21 | Gautier | 18,996 | -0.0% | 
| 22 | Ocean Springs | 18,387 | -0.1% | 
| 23 | Hernando | 17,345 | 1.6% | 
| 24 | Laurel | 17,106 | -0.2% | 
| 25 | Long Beach | 16,856 | 0.5% | 
| 26 | Clarksdale | 14,410 | -2.3% | 
| 27 | Corinth | 14,382 | -1.2% | 
| 28 | Greenwood | 14,037 | -2.5% | 
| 29 | Natchez | 13,824 | -2.7% | 
| 30 | D'Iberville | 13,236 | 4.3% | 
| 31 | Grenada | 12,471 | -1.2% | 
| 32 | Byram | 12,456 | -1.3% | 
| 33 | McComb | 12,217 | -1.1% | 
| 34 | Moss Point | 12,039 | -0.6% | 
| 35 | Brookhaven | 11,812 | 0.8% | 
| 36 | Picayune | 11,784 | -0.6% | 
| 37 | Petal | 11,505 | 0.7% | 
| 38 | Cleveland | 10,909 | -2.0% | 
| 39 | Canton | 10,688 | -0.9% | 
| 40 | Flowood | 10,373 | 1.4% | 
| 41 | Yazoo City | 10,163 | -1.4% | 
| 42 | Bay St. Louis | 10,009 | 5.8% | 
| 43 | West Point | 9,983 | -0.9% | 
| 44 | Diamondhead | 9,442 | -1.3% | 
| 45 | Indianola | 9,342 | -1.9% | 
| 46 | Booneville | 8,681 | -0.1% | 
| 47 | Senatobia | 8,099 | 0.1% | 
| 48 | New Albany | 7,618 | 0.4% | 
| 49 | Batesville | 7,326 | -1.2% | 
| 50 | Richland | 7,180 | 0.9% | 
| 51 | Waveland | 7,038 | -1.7% | 
| 52 | Kosciusko | 7,022 | -1.0% | 
| 53 | Philadelphia | 6,995 | -0.6% | 
| 54 | Holly Springs | 6,565 | -1.2% | 
| 55 | Amory | 6,513 | -1.1% | 
| 56 | Louisville | 6,008 | -0.7% | 
| 57 | Columbia | 5,914 | -0.6% | 
| 58 | Pass Christian | 5,882 | 2.5% | 
| 59 | Carthage | 5,707 | -0.5% | 
| 60 | Pontotoc | 5,684 | 1.5% | 
| 61 | Ripley | 5,362 | -0.5% | 
| 62 | Forest | 5,339 | -1.4% | 
| 63 | Saltillo | 4,910 | -0.2% | 
| 64 | Aberdeen | 4,856 | -0.9% | 
| 65 | Crystal Springs | 4,768 | -1.5% | 
| 66 | Florence | 4,623 | 1.2% | 
| 67 | Waynesboro | 4,541 | -0.2% | 
| 68 | Ellisville | 4,510 | -0.9% | 
| 69 | Winona | 4,339 | -2.6% | 
| 70 | Wiggins | 4,289 | 0.8% | 
| 71 | Fulton | 4,022 | -0.4% | 
| 72 | Leland | 3,888 | -2.3% | 
| 73 | Magee | 3,888 | -1.0% | 
| 74 | Houston | 3,772 | -0.6% | 
| 75 | Morton | 3,615 | -1.6% | 
| 76 | Leakesville | 3,603 | 0.4% | 
| 77 | Hazlehurst | 3,552 | -1.5% | 
| 78 | Water Valley | 3,301 | -0.2% | 
| 79 | Newton | 3,137 | -1.4% | 
| 80 | Baldwyn | 3,118 | -0.0% | 
| 81 | Iuka | 3,066 | -0.5% | 
| 82 | Lucedale | 2,934 | 1.6% | 
| 83 | Tutwiler | 2,900 | -0.9% | 
| 84 | Poplarville | 2,822 | -0.5% | 
| 85 | Verona | 2,773 | -0.9% | 
| 86 | Ruleville | 2,572 | -1.8% | 
| 87 | Macon | 2,523 | -1.4% | 
| 88 | Okolona | 2,487 | -0.5% | 
| 89 | Guntown | 2,415 | 0.0% | 
| 90 | Hollandale | 2,277 | -2.2% | 
| 91 | Collins | 2,242 | -0.4% | 
| 92 | Mendenhall | 2,181 | -1.0% | 
| 93 | Durant | 2,145 | -3.2% | 
| 94 | Farmington | 2,031 | -1.2% | 
| 95 | Shelby | 1,975 | -2.1% | 
| 96 | Union | 1,972 | -1.0% | 
| 97 | Quitman | 1,964 | -1.3% | 
| 98 | Eupora | 1,949 | 0.4% | 
| 99 | Purvis | 1,921 | 1.6% | 
| 100 | Moorhead | 1,909 | -1.6% | 
© 2025 www.biggestuscities.com, All Rights Reserved • Privacy Policy • Last updated: Jan 2, 2025