| Rank | City | 2012 Population (Est.) | Growth Rate (Annual) |
|---|---|---|---|
| 1 | Jackson | 175,291 | 1.0% |
| 2 | Gulfport | 68,915 | 1.7% |
| 3 | Southaven | 49,687 | 1.4% |
| 4 | Hattiesburg | 46,617 | 1.4% |
| 5 | Biloxi | 44,239 | 0.4% |
| 6 | Meridian | 41,096 | -0.1% |
| 7 | Tupelo | 35,127 | 1.7% |
| 8 | Olive Branch | 34,028 | 1.6% |
| 9 | Greenville | 33,907 | -1.4% |
| 10 | Horn Lake | 26,303 | 0.9% |
| 11 | Pearl | 25,961 | 3.5% |
| 12 | Clinton | 25,694 | 1.9% |
| 13 | Madison | 24,577 | 1.8% |
| 14 | Ridgeland | 24,144 | 0.4% |
| 15 | Starkville | 24,089 | 0.8% |
| 16 | Vicksburg | 23,548 | -1.3% |
| 17 | Columbus | 23,547 | -0.4% |
| 18 | Pascagoula | 22,339 | -0.2% |
| 19 | Brandon | 21,888 | 0.8% |
| 20 | Oxford | 19,479 | 3.0% |
| 21 | Gautier | 18,616 | 0.2% |
| 22 | Laurel | 18,585 | 0.2% |
| 23 | Clarksdale | 17,751 | -1.2% |
| 24 | Ocean Springs | 17,458 | 0.1% |
| 25 | Natchez | 15,649 | -0.9% |
| 26 | Long Beach | 15,172 | 2.6% |
| 27 | Greenwood | 14,981 | -1.5% |
| 28 | Corinth | 14,779 | 1.4% |
| 29 | Hernando | 14,446 | 2.5% |
| 30 | Moss Point | 13,736 | 0.2% |
| 31 | Canton | 13,200 | 0.1% |
| 32 | Grenada | 12,936 | -1.2% |
| 33 | McComb | 12,850 | 0.5% |
| 34 | Brookhaven | 12,516 | 0.0% |
| 35 | Cleveland | 12,124 | -1.7% |
| 36 | Byram | 11,660 | 1.5% |
| 37 | Yazoo City | 11,544 | 1.2% |
| 38 | West Point | 11,246 | -0.5% |
| 39 | Picayune | 10,963 | 0.8% |
| 40 | Petal | 10,633 | 1.7% |
| 41 | Indianola | 10,585 | -0.9% |
| 42 | D'Iberville | 9,904 | 4.4% |
| 43 | Bay St. Louis | 9,780 | 5.6% |
| 44 | Booneville | 8,772 | 0.3% |
| 45 | Senatobia | 8,119 | -0.6% |
| 46 | New Albany | 8,077 | 0.5% |
| 47 | Flowood | 8,029 | 2.6% |
| 48 | Holly Springs | 7,598 | -1.3% |
| 49 | Philadelphia | 7,475 | -0.0% |
| 50 | Batesville | 7,434 | -0.4% |
| 51 | Kosciusko | 7,302 | -1.4% |
| 52 | Amory | 7,232 | -1.1% |
| 53 | Richland | 7,002 | 1.3% |
| 54 | Louisville | 6,564 | -1.0% |
| 55 | Columbia | 6,496 | -1.3% |
| 56 | Waveland | 6,484 | 0.8% |
| 57 | Forest | 5,722 | 0.7% |
| 58 | Pontotoc | 5,648 | 0.4% |
| 59 | Aberdeen | 5,533 | -1.4% |
| 60 | Ripley | 5,366 | -0.5% |
| 61 | Waynesboro | 5,009 | -0.7% |
| 62 | Carthage | 5,003 | -1.4% |
| 63 | Crystal Springs | 5,003 | -0.8% |
| 64 | Winona | 4,954 | -1.8% |
| 65 | Saltillo | 4,840 | 1.9% |
| 66 | Pass Christian | 4,780 | 3.6% |
| 67 | Ellisville | 4,585 | 3.1% |
| 68 | Leland | 4,423 | -1.3% |
| 69 | Wiggins | 4,414 | 0.5% |
| 70 | Magee | 4,402 | -0.1% |
| 71 | Florence | 4,213 | 1.7% |
| 72 | Hazlehurst | 3,976 | -0.8% |
| 73 | Fulton | 3,973 | 0.3% |
| 74 | Houston | 3,572 | -1.4% |
| 75 | Tutwiler | 3,548 | -0.1% |
| 76 | Morton | 3,455 | -0.2% |
| 77 | Water Valley | 3,358 | -1.0% |
| 78 | Newton | 3,345 | -0.8% |
| 79 | Baldwyn | 3,313 | 0.5% |
| 80 | Verona | 3,054 | 1.6% |
| 81 | Iuka | 3,025 | -0.1% |
| 82 | Ruleville | 2,980 | -0.9% |
| 83 | Lucedale | 2,929 | 0.2% |
| 84 | Poplarville | 2,864 | -1.0% |
| 85 | Macon | 2,713 | -2.0% |
| 86 | Hollandale | 2,685 | -0.6% |
| 87 | Okolona | 2,648 | -1.6% |
| 88 | Durant | 2,627 | -1.7% |
| 89 | Collins | 2,587 | 0.0% |
| 90 | Mendenhall | 2,486 | -0.7% |
| 91 | Magnolia | 2,405 | -0.6% |
| 92 | Moorhead | 2,391 | -0.6% |
| 93 | Quitman | 2,318 | -0.2% |
| 94 | Purvis | 2,224 | 2.3% |
| 95 | Guntown | 2,222 | 6.7% |
| 96 | Belzoni | 2,217 | -0.8% |
| 97 | Shelby | 2,204 | -1.1% |
| 98 | Farmington | 2,182 | -0.2% |
| 99 | Charleston | 2,180 | -0.6% |
| 100 | Eupora | 2,162 | -1.6% |
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