| Rank | City | 2020 Population | Growth Rate (Annual) |
|---|---|---|---|
| 1 | Louisville | 632,037 | 0.6% |
| 2 | Lexington | 322,403 | 0.9% |
| 3 | Bowling Green | 72,642 | 2.3% |
| 4 | Owensboro | 60,183 | 0.5% |
| 5 | Covington | 41,018 | 0.1% |
| 6 | Georgetown | 37,253 | 2.5% |
| 7 | Richmond | 34,838 | 1.1% |
| 8 | Florence | 31,924 | 0.6% |
| 9 | Elizabethtown | 31,433 | 1.0% |
| 10 | Nicholasville | 31,103 | 1.1% |
| 11 | Hopkinsville | 30,839 | -0.2% |
| 12 | Jeffersontown | 28,824 | 0.8% |
| 13 | Independence | 28,632 | 1.5% |
| 14 | Frankfort | 28,631 | 1.2% |
| 15 | Henderson | 27,931 | -0.3% |
| 16 | Paducah | 26,508 | 0.6% |
| 17 | Radcliff | 22,953 | 0.6% |
| 18 | Ashland | 21,653 | -0.0% |
| 19 | Erlanger | 19,641 | 0.8% |
| 20 | Madisonville | 19,549 | -0.0% |
| 21 | Winchester | 19,153 | 0.4% |
| 22 | Mount Washington | 18,195 | 7.2% |
| 23 | St. Matthews | 17,534 | 0.0% |
| 24 | Fort Thomas | 17,370 | 0.6% |
| 25 | Danville | 17,283 | 0.6% |
| 26 | Shelbyville | 17,278 | 2.1% |
| 27 | Murray | 17,118 | -0.4% |
| 28 | Berea | 15,625 | 1.4% |
| 29 | Shively | 15,619 | 0.2% |
| 30 | Glasgow | 14,981 | 0.7% |
| 31 | Shepherdsville | 14,217 | 2.4% |
| 32 | Newport | 14,210 | -0.7% |
| 33 | Bardstown | 13,531 | 1.5% |
| 34 | Somerset | 11,742 | 0.5% |
| 35 | Lawrenceburg | 11,735 | 1.1% |
| 36 | Campbellsville | 11,371 | 2.2% |
| 37 | Lyndon | 10,980 | -0.0% |
| 38 | Versailles | 10,364 | 1.9% |
| 39 | Alexandria | 10,322 | 2.0% |
| 40 | Paris | 10,244 | 1.8% |
| 41 | Franklin | 10,092 | 1.8% |
| 42 | La Grange | 10,021 | 2.2% |
| 43 | Mayfield | 9,976 | -0.0% |
| 44 | Middletown | 9,694 | 3.0% |
| 45 | Middlesborough | 9,333 | -1.0% |
| 46 | Elsmere | 9,173 | 0.8% |
| 47 | Harrodsburg | 9,025 | 0.8% |
| 48 | Maysville | 8,851 | -0.2% |
| 49 | Fort Mitchell | 8,681 | 0.6% |
| 50 | Hillview | 8,617 | 0.5% |
| 51 | Edgewood | 8,402 | -0.2% |
| 52 | Oak Grove | 7,776 | 0.4% |
| 53 | Corbin | 7,774 | 0.6% |
| 54 | Mount Sterling | 7,546 | 0.9% |
| 55 | Union | 7,475 | 3.3% |
| 56 | Pikeville | 7,467 | 0.8% |
| 57 | London | 7,425 | -0.7% |
| 58 | Villa Hills | 7,325 | -0.2% |
| 59 | Flatwoods | 7,291 | -0.2% |
| 60 | Russellville | 7,124 | 0.2% |
| 61 | Morehead | 6,996 | 0.2% |
| 62 | Taylor Mill | 6,843 | 0.4% |
| 63 | Highland Heights | 6,840 | -0.1% |
| 64 | Vine Grove | 6,560 | 3.8% |
| 65 | Leitchfield | 6,385 | -0.5% |
| 66 | Cynthiana | 6,294 | -0.2% |
| 67 | Lebanon | 6,239 | 1.2% |
| 68 | Princeton | 6,217 | -0.2% |
| 69 | Cold Spring | 6,214 | 0.5% |
| 70 | Crestwood | 6,161 | 3.1% |
| 71 | Wilmore | 5,973 | 4.9% |
| 72 | Central City | 5,940 | -0.1% |
| 73 | Fort Wright | 5,855 | 0.2% |
| 74 | Monticello | 5,703 | -0.8% |
| 75 | Dayton | 5,661 | 0.6% |
| 76 | Bellevue | 5,514 | -0.8% |
| 77 | Walton | 5,494 | 4.2% |
| 78 | Douglass Hills | 5,449 | -0.1% |
| 79 | Williamsburg | 5,296 | 0.1% |
| 80 | Hazard | 5,213 | 1.6% |
| 81 | Columbia | 4,997 | 1.2% |
| 82 | Benton | 4,755 | 0.9% |
| 83 | Hurstbourne | 4,677 | 1.0% |
| 84 | Prospect | 4,586 | -0.2% |
| 85 | Greenville | 4,514 | 0.5% |
| 86 | Paintsville | 4,381 | 2.4% |
| 87 | Ludlow | 4,377 | -0.1% |
| 88 | Crescent Springs | 4,312 | 1.3% |
| 89 | Scottsville | 4,290 | 0.2% |
| 90 | Prestonsburg | 4,151 | 2.5% |
| 91 | Crittenden | 4,021 | 0.5% |
| 92 | Williamstown | 3,937 | 0.0% |
| 93 | Carrollton | 3,892 | -0.1% |
| 94 | Lancaster | 3,834 | 1.1% |
| 95 | Grayson | 3,737 | -1.2% |
| 96 | Russell | 3,716 | 1.0% |
| 97 | Southgate | 3,634 | -0.5% |
| 98 | Stanford | 3,623 | 0.4% |
| 99 | Beaver Dam | 3,534 | 0.4% |
| 100 | Crestview Hills | 3,412 | 0.8% |
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