| Rank | City | 2008 Population (Est.) | Growth Rate (Annual) |
|---|---|---|---|
| 1 | Louisville | 562,632 | 0.2% |
| 2 | Lexington | 287,263 | 1.4% |
| 3 | Owensboro | 55,409 | 0.3% |
| 4 | Bowling Green | 54,659 | 1.4% |
| 5 | Covington | 42,747 | -0.1% |
| 6 | Richmond | 32,489 | 2.3% |
| 7 | Hopkinsville | 31,638 | 0.7% |
| 8 | Henderson | 27,637 | 0.1% |
| 9 | Florence | 27,329 | 2.0% |
| 10 | Frankfort | 27,135 | -0.3% |
| 11 | Jeffersontown | 26,209 | -0.2% |
| 12 | Nicholasville | 25,906 | 3.2% |
| 13 | Paducah | 25,563 | -0.4% |
| 14 | Elizabethtown | 23,736 | 0.7% |
| 15 | Radcliff | 21,998 | -0.1% |
| 16 | Ashland | 21,361 | -0.4% |
| 17 | Independence | 21,124 | 4.8% |
| 18 | Georgetown | 21,104 | 1.9% |
| 19 | Madisonville | 19,008 | -0.2% |
| 20 | St. Matthews | 18,135 | 0.7% |
| 21 | Erlanger | 17,128 | 0.4% |
| 22 | Winchester | 16,635 | -0.1% |
| 23 | Murray | 16,279 | 0.9% |
| 24 | Shively | 15,835 | 0.9% |
| 25 | Newport | 15,596 | -1.2% |
| 26 | Danville | 15,517 | 0.0% |
| 27 | Fort Thomas | 15,291 | -1.1% |
| 28 | Berea | 14,238 | 3.3% |
| 29 | Glasgow | 14,106 | 1.0% |
| 30 | Somerset | 12,078 | 0.8% |
| 31 | Mount Washington | 11,878 | 4.5% |
| 32 | Shelbyville | 11,195 | 1.3% |
| 33 | Bardstown | 11,122 | 0.4% |
| 34 | Campbellsville | 11,121 | 0.9% |
| 35 | Lyndon | 10,774 | 0.9% |
| 36 | Mayfield | 10,180 | -0.2% |
| 37 | Lawrenceburg | 9,929 | 1.2% |
| 38 | Middlesborough | 9,876 | -0.7% |
| 39 | Oak Grove | 9,450 | 4.2% |
| 40 | Paris | 9,176 | -0.0% |
| 41 | Shepherdsville | 9,165 | 1.1% |
| 42 | Maysville | 9,135 | 0.3% |
| 43 | Edgewood | 8,898 | -0.8% |
| 44 | Alexandria | 8,334 | -0.4% |
| 45 | Corbin | 8,194 | 0.6% |
| 46 | Harrodsburg | 8,159 | 0.0% |
| 47 | Franklin | 8,032 | -0.2% |
| 48 | Elsmere | 7,937 | -0.4% |
| 49 | London | 7,856 | 0.8% |
| 50 | Versailles | 7,818 | -0.2% |
| 51 | Villa Hills | 7,720 | -0.4% |
| 52 | Morehead | 7,638 | 0.1% |
| 53 | Fort Mitchell | 7,567 | -0.9% |
| 54 | Flatwoods | 7,558 | 0.1% |
| 55 | Hillview | 7,423 | 0.8% |
| 56 | Russellville | 7,251 | 0.2% |
| 57 | Taylor Mill | 7,127 | -0.4% |
| 58 | Highland Heights | 6,980 | 0.3% |
| 59 | Mount Sterling | 6,854 | 1.6% |
| 60 | Middletown | 6,707 | 2.0% |
| 61 | La Grange | 6,476 | 1.8% |
| 62 | Leitchfield | 6,471 | 0.5% |
| 63 | Princeton | 6,361 | -0.4% |
| 64 | Pikeville | 6,353 | -0.3% |
| 65 | Lebanon | 6,288 | 0.9% |
| 66 | Cynthiana | 6,265 | -0.2% |
| 67 | Monticello | 6,121 | 0.3% |
| 68 | Bellevue | 5,889 | -1.3% |
| 69 | Douglass Hills | 5,888 | 0.8% |
| 70 | Wilmore | 5,746 | -0.4% |
| 71 | Central City | 5,728 | -0.4% |
| 72 | Cold Spring | 5,720 | 5.5% |
| 73 | Dayton | 5,478 | -1.2% |
| 74 | Fort Wright | 5,446 | -0.6% |
| 75 | Prospect | 5,425 | 2.3% |
| 76 | Williamsburg | 5,117 | 0.5% |
| 77 | Ludlow | 4,837 | 1.4% |
| 78 | Hazard | 4,761 | -0.3% |
| 79 | Columbia | 4,563 | 0.5% |
| 80 | Scottsville | 4,516 | 0.6% |
| 81 | Lancaster | 4,379 | 1.9% |
| 82 | Benton | 4,366 | 0.1% |
| 83 | Greenville | 4,298 | -0.3% |
| 84 | Hurstbourne | 4,227 | 1.2% |
| 85 | Paintsville | 4,179 | 0.2% |
| 86 | Vine Grove | 4,179 | 0.1% |
| 87 | Crescent Springs | 4,050 | 0.4% |
| 88 | Grayson | 3,955 | 0.3% |
| 89 | Carrollton | 3,857 | 0.1% |
| 90 | Prestonsburg | 3,826 | -0.1% |
| 91 | Crestview Hills | 3,595 | 3.0% |
| 92 | Russell | 3,581 | -0.2% |
| 93 | Union | 3,548 | 2.8% |
| 94 | Barbourville | 3,532 | -0.2% |
| 95 | Williamstown | 3,471 | 0.9% |
| 96 | Providence | 3,463 | -0.6% |
| 97 | Stanford | 3,407 | -0.1% |
| 98 | West Liberty | 3,384 | 0.6% |
| 99 | Morganfield | 3,310 | -0.7% |
| 100 | Southgate | 3,291 | -0.8% |
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