| Rank | City | 2004 Population (Est.) | Growth Rate (Annual) |
|---|---|---|---|
| 1 | Louisville | 557,113 | 0.2% |
| 2 | Lexington | 271,441 | 1.3% |
| 3 | Owensboro | 54,263 | 0.0% |
| 4 | Bowling Green | 51,291 | 1.2% |
| 5 | Covington | 42,816 | -0.1% |
| 6 | Hopkinsville | 30,874 | 0.8% |
| 7 | Richmond | 29,396 | 2.0% |
| 8 | Frankfort | 27,408 | -0.4% |
| 9 | Henderson | 27,399 | -0.1% |
| 10 | Jeffersontown | 26,375 | -0.2% |
| 11 | Paducah | 25,531 | -0.9% |
| 12 | Florence | 24,788 | 1.5% |
| 13 | Elizabethtown | 23,088 | 0.7% |
| 14 | Nicholasville | 22,766 | 3.0% |
| 15 | Radcliff | 21,785 | -0.5% |
| 16 | Ashland | 21,608 | -0.5% |
| 17 | Georgetown | 19,528 | 1.8% |
| 18 | Madisonville | 19,166 | -0.3% |
| 19 | St. Matthews | 17,371 | 0.1% |
| 20 | Independence | 16,946 | 3.7% |
| 21 | Erlanger | 16,720 | 0.1% |
| 22 | Newport | 16,367 | -1.3% |
| 23 | Winchester | 16,361 | -0.8% |
| 24 | Fort Thomas | 15,952 | -1.1% |
| 25 | Murray | 15,482 | 0.5% |
| 26 | Danville | 15,277 | -0.4% |
| 27 | Shively | 15,004 | 0.2% |
| 28 | Glasgow | 13,603 | 1.2% |
| 29 | Berea | 12,454 | 3.2% |
| 30 | Somerset | 11,680 | 0.8% |
| 31 | Bardstown | 10,812 | 0.0% |
| 32 | Campbellsville | 10,727 | 0.8% |
| 33 | Shelbyville | 10,441 | 0.8% |
| 34 | Mayfield | 10,203 | -0.5% |
| 35 | Lyndon | 10,186 | 0.3% |
| 36 | Middlesborough | 10,154 | -0.7% |
| 37 | Mount Washington | 10,094 | 5.0% |
| 38 | Lawrenceburg | 9,239 | 0.3% |
| 39 | Paris | 9,194 | 0.0% |
| 40 | Edgewood | 9,115 | -1.0% |
| 41 | Maysville | 8,866 | -0.4% |
| 42 | Shepherdsville | 8,750 | 0.9% |
| 43 | Oak Grove | 8,608 | 6.7% |
| 44 | Alexandria | 8,345 | -0.8% |
| 45 | Harrodsburg | 8,163 | 0.0% |
| 46 | Elsmere | 8,052 | -0.4% |
| 47 | Franklin | 8,020 | -0.5% |
| 48 | Corbin | 7,944 | 0.3% |
| 49 | Villa Hills | 7,845 | -0.4% |
| 50 | Versailles | 7,828 | -0.3% |
| 51 | Fort Mitchell | 7,800 | -1.1% |
| 52 | London | 7,654 | 0.9% |
| 53 | Morehead | 7,603 | – |
| 54 | Flatwoods | 7,493 | -0.1% |
| 55 | Taylor Mill | 7,230 | -0.5% |
| 56 | Hillview | 7,155 | 0.5% |
| 57 | Russellville | 7,113 | -0.2% |
| 58 | Highland Heights | 6,769 | -0.3% |
| 59 | Pikeville | 6,496 | 0.1% |
| 60 | Princeton | 6,375 | -0.8% |
| 61 | Leitchfield | 6,311 | 0.4% |
| 62 | Cynthiana | 6,242 | -0.5% |
| 63 | Mount Sterling | 6,240 | 0.6% |
| 64 | Bellevue | 6,200 | -1.4% |
| 65 | Monticello | 6,040 | 0.3% |
| 66 | La Grange | 5,991 | 1.6% |
| 67 | Middletown | 5,987 | 0.9% |
| 68 | Lebanon | 5,964 | 0.4% |
| 69 | Wilmore | 5,793 | -0.6% |
| 70 | Central City | 5,762 | -0.7% |
| 71 | Dayton | 5,718 | -1.4% |
| 72 | Douglass Hills | 5,595 | 0.3% |
| 73 | Fort Wright | 5,550 | -0.8% |
| 74 | Williamsburg | 4,994 | 0.3% |
| 75 | Hazard | 4,794 | -0.5% |
| 76 | Prospect | 4,771 | 1.0% |
| 77 | Cold Spring | 4,730 | 6.3% |
| 78 | Columbia | 4,539 | 1.0% |
| 79 | Scottsville | 4,368 | 0.3% |
| 80 | Ludlow | 4,353 | -0.4% |
| 81 | Greenville | 4,332 | -0.4% |
| 82 | Benton | 4,296 | -0.4% |
| 83 | Paintsville | 4,134 | 0.1% |
| 84 | Lancaster | 4,074 | 2.1% |
| 85 | Vine Grove | 4,036 | -1.0% |
| 86 | Grayson | 3,985 | 0.9% |
| 87 | Crescent Springs | 3,970 | 0.2% |
| 88 | Hurstbourne | 3,931 | 0.4% |
| 89 | Carrollton | 3,823 | -0.2% |
| 90 | Prestonsburg | 3,810 | -0.5% |
| 91 | Russell | 3,585 | -0.5% |
| 92 | Providence | 3,512 | -0.9% |
| 93 | Barbourville | 3,497 | -0.8% |
| 94 | Southgate | 3,415 | -0.6% |
| 95 | Morganfield | 3,403 | -0.7% |
| 96 | Stanford | 3,384 | -0.4% |
| 97 | Williamstown | 3,360 | 1.1% |
| 98 | West Liberty | 3,354 | 1.1% |
| 99 | Crestview Hills | 3,211 | 3.2% |
| 100 | Union | 3,134 | 2.3% |
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