| Rank | City | 2017 Population (Est.) | Growth Rate (Annual) |
|---|---|---|---|
| 1 | Des Moines | 215,472 | 1.0% |
| 2 | Cedar Rapids | 131,127 | 0.6% |
| 3 | Davenport | 102,612 | 0.5% |
| 4 | Sioux City | 82,872 | 0.0% |
| 5 | Iowa City | 74,398 | 1.5% |
| 6 | Waterloo | 67,934 | -0.1% |
| 7 | Ames | 66,191 | 1.9% |
| 8 | West Des Moines | 64,560 | 2.2% |
| 9 | Council Bluffs | 62,524 | 0.1% |
| 10 | Ankeny | 58,627 | 4.3% |
| 11 | Dubuque | 58,531 | 0.3% |
| 12 | Urbandale | 43,018 | 1.4% |
| 13 | Cedar Falls | 41,390 | 0.9% |
| 14 | Marion | 38,480 | 1.7% |
| 15 | Bettendorf | 35,727 | 1.2% |
| 16 | Mason City | 27,430 | -0.4% |
| 17 | Marshalltown | 27,328 | -0.1% |
| 18 | Clinton | 25,719 | -0.7% |
| 19 | Burlington | 25,277 | -0.3% |
| 20 | Ottumwa | 24,487 | -0.4% |
| 21 | Fort Dodge | 24,441 | -0.5% |
| 22 | Muscatine | 23,914 | 0.7% |
| 23 | Johnston | 21,114 | 3.4% |
| 24 | Coralville | 20,397 | 1.3% |
| 25 | Waukee | 19,284 | 5.7% |
| 26 | North Liberty | 18,520 | 5.6% |
| 27 | Altoona | 17,938 | 3.6% |
| 28 | Clive | 17,546 | 2.1% |
| 29 | Indianola | 15,785 | 1.1% |
| 30 | Newton | 15,034 | -0.2% |
| 31 | Boone | 12,611 | -0.1% |
| 32 | Grimes | 11,909 | 6.3% |
| 33 | Oskaloosa | 11,523 | 0.1% |
| 34 | Spencer | 11,138 | -0.1% |
| 35 | Storm Lake | 10,773 | 0.3% |
| 36 | Fort Madison | 10,597 | -0.7% |
| 37 | Norwalk | 10,590 | 2.9% |
| 38 | Keokuk | 10,431 | -0.5% |
| 39 | Pella | 10,255 | -0.2% |
| 40 | Fairfield | 10,206 | 1.3% |
| 41 | Waverly | 10,093 | 0.4% |
| 42 | Carroll | 9,947 | -0.3% |
| 43 | Le Mars | 9,935 | 0.2% |
| 44 | Pleasant Hill | 9,750 | 1.8% |
| 45 | Grinnell | 9,151 | -0.1% |
| 46 | Mount Pleasant | 8,392 | -0.5% |
| 47 | Denison | 8,308 | 0.0% |
| 48 | Decorah | 7,918 | -0.4% |
| 49 | Creston | 7,829 | -0.0% |
| 50 | Perry | 7,810 | 0.2% |
| 51 | Webster City | 7,756 | -0.7% |
| 52 | Clear Lake | 7,589 | -0.4% |
| 53 | Sioux Center | 7,501 | 1.0% |
| 54 | Charles City | 7,457 | -0.4% |
| 55 | Washington | 7,424 | 0.4% |
| 56 | Knoxville | 7,241 | -0.2% |
| 57 | Hiawatha | 7,212 | 0.4% |
| 58 | Nevada | 6,805 | 0.0% |
| 59 | Atlantic | 6,659 | -1.1% |
| 60 | Eldridge | 6,297 | 1.8% |
| 61 | Orange City | 6,179 | 0.5% |
| 62 | Oelwein | 6,056 | -1.0% |
| 63 | Independence | 6,018 | 0.1% |
| 64 | Maquoketa | 5,979 | -0.4% |
| 65 | Estherville | 5,942 | -1.1% |
| 66 | Bondurant | 5,796 | 7.0% |
| 67 | Algona | 5,515 | -0.1% |
| 68 | Red Oak | 5,476 | -0.8% |
| 69 | Asbury | 5,475 | 4.6% |
| 70 | Anamosa | 5,430 | -0.3% |
| 71 | Clarinda | 5,385 | -0.6% |
| 72 | Centerville | 5,345 | -0.6% |
| 73 | Glenwood | 5,309 | 0.1% |
| 74 | Winterset | 5,271 | 0.3% |
| 75 | De Witt | 5,233 | -0.3% |
| 76 | Vinton | 5,143 | -0.4% |
| 77 | Iowa Falls | 5,128 | -0.4% |
| 78 | Sheldon | 5,115 | -0.2% |
| 79 | Spirit Lake | 5,086 | 0.8% |
| 80 | Manchester | 5,053 | -0.4% |
| 81 | Osceola | 5,037 | 0.4% |
| 82 | Cherokee | 4,998 | -0.8% |
| 83 | Windsor Heights | 4,983 | 0.4% |
| 84 | Shenandoah | 4,972 | -0.6% |
| 85 | Harlan | 4,932 | -0.6% |
| 86 | Evansdale | 4,786 | 0.1% |
| 87 | Humboldt | 4,558 | -0.5% |
| 88 | Sergeant Bluff | 4,551 | 1.2% |
| 89 | Mount Vernon | 4,444 | -0.2% |
| 90 | Polk City | 4,428 | 4.4% |
| 91 | Camanche | 4,325 | -0.5% |
| 92 | Adel | 4,293 | 2.6% |
| 93 | Carlisle | 4,249 | 1.5% |
| 94 | Hampton | 4,239 | -0.8% |
| 95 | Dyersville | 4,196 | 0.6% |
| 96 | Chariton | 4,191 | -0.5% |
| 97 | Jefferson | 4,169 | -0.7% |
| 98 | Forest City | 4,013 | -0.6% |
| 99 | Le Claire | 3,974 | 0.9% |
| 100 | Monticello | 3,836 | 0.2% |
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