Rank School District Population (2012)
1 Greenville County School District, South Carolina 469,054
2 Charleston County School District, South Carolina 351,945
3 Horry County School District, South Carolina 270,875
4 Berkeley County School District, South Carolina 179,127
5 Aiken County School District, South Carolina 162,347
6 Beaufort County School District, South Carolina 160,762
7 Richland School District 2, South Carolina 126,568
8 Dorchester School District 2, South Carolina 121,398
9 Pickens County School District, South Carolina 119,313
10 Florence School District 1, South Carolina 99,802
11 Lexington School District 5, South Carolina 91,722
12 Lancaster County School District, South Carolina 76,755
13 Oconee County School District, South Carolina 74,217
14 Darlington County School District, South Carolina 68,547
15 Kershaw County School District, South Carolina 61,758
16 Georgetown County School District, South Carolina 60,167
17 Greenwood School District 50, South Carolina 58,195
18 Spartanburg School District 6, South Carolina 55,182
19 Cherokee County School District, South Carolina 53,068
20 Sumter School District 17, South Carolina 51,776
21 Anderson School District 1, South Carolina 46,691
22 Chesterfield County School District, South Carolina 46,621
23 Colleton County School District, South Carolina 38,796
24 Newberry County School District, South Carolina 37,574
25 Williamsburg County School District, South Carolina 34,354
26 Chester County School District, South Carolina 33,082
27 York School District 1, South Carolina 30,749
28 Union County School District, South Carolina 28,892
29 Marlboro County School District, South Carolina 28,862
30 Edgefield County School District, South Carolina 26,881
31 Jasper County School District, South Carolina 24,795
32 Abbeville County School District, South Carolina 24,749
33 Fairfield County School District, South Carolina 23,844
34 Orangeburg School District 3, South Carolina 21,729
35 Laurens School District 56, South Carolina 19,633
36 Lee County School District, South Carolina 19,176
37 Clarendon School District 2, South Carolina 18,890
38 Calhoun County School District, South Carolina 15,198
39 Remainder of South Carolina, South Carolina 15,119
40 Saluda County School District, South Carolina 14,491
41 Marion School District 2, South Carolina 11,540
42 Barnwell School District 45, South Carolina 11,510
43 Allendale County School District, South Carolina 10,548
44 McCormick County School District, South Carolina 10,178
45 Hampton School District 2, South Carolina 8,061
46 Bamberg School District 2, South Carolina 7,693
47 Dillon School District 1, South Carolina 5,164

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