| Rank | City | 2022 Population (Est.) | Growth Rate (Annual) |
|---|---|---|---|
| 1 | Charlotte | 879,709 | 0.3% |
| 2 | Raleigh | 469,124 | 0.4% |
| 3 | Greensboro | 298,263 | 0.2% |
| 4 | Durham | 285,527 | 0.4% |
| 5 | Winston-Salem | 250,320 | 0.4% |
| 6 | Fayetteville | 208,778 | 0.1% |
| 7 | Cary | 176,987 | 0.9% |
| 8 | Wilmington | 117,643 | 1.3% |
| 9 | High Point | 114,086 | 0.2% |
| 10 | Concord | 107,697 | 1.8% |
| 11 | Asheville | 94,067 | -0.4% |
| 12 | Greenville | 88,728 | 0.7% |
| 13 | Gastonia | 81,161 | 1.0% |
| 14 | Jacksonville | 72,876 | -0.4% |
| 15 | Apex | 62,911 | 4.9% |
| 16 | Huntersville | 61,839 | 0.4% |
| 17 | Chapel Hill | 61,128 | -0.2% |
| 18 | Burlington | 58,818 | 2.1% |
| 19 | Kannapolis | 54,446 | 1.9% |
| 20 | Rocky Mount | 53,957 | -0.5% |
| 21 | Mooresville | 51,594 | 2.3% |
| 22 | Wake Forest | 49,657 | 3.5% |
| 23 | Wilson | 47,731 | -0.4% |
| 24 | Hickory | 43,532 | 0.5% |
| 25 | Holly Springs | 43,524 | 4.3% |
| 26 | Indian Trail | 40,953 | 1.7% |
| 27 | Fuquay-Varina | 36,736 | 6.3% |
| 28 | Salisbury | 35,760 | 0.5% |
| 29 | Monroe | 34,888 | 0.9% |
| 30 | Goldsboro | 32,749 | -0.9% |
| 31 | Garner | 31,935 | 2.0% |
| 32 | Cornelius | 31,650 | 0.4% |
| 33 | New Bern | 31,346 | 0.9% |
| 34 | Morrisville | 31,278 | 4.2% |
| 35 | Sanford | 30,678 | 1.3% |
| 36 | Matthews | 29,623 | 0.4% |
| 37 | Statesville | 28,844 | 2.1% |
| 38 | Clayton | 28,306 | 6.1% |
| 39 | Thomasville | 27,203 | 0.2% |
| 40 | Asheboro | 27,124 | 0.6% |
| 41 | Kernersville | 26,793 | 1.1% |
| 42 | Mint Hill | 26,633 | 0.4% |
| 43 | Leland | 25,974 | 8.6% |
| 44 | Shelby | 21,947 | 0.2% |
| 45 | Waxhaw | 21,673 | 4.3% |
| 46 | Clemmons | 21,517 | 1.4% |
| 47 | Carrboro | 21,312 | -0.6% |
| 48 | Knightdale | 19,576 | 0.4% |
| 49 | Kinston | 19,546 | -1.0% |
| 50 | Lexington | 19,516 | 0.1% |
| 51 | Harrisburg | 19,463 | 1.9% |
| 52 | Elizabeth City | 18,703 | 0.3% |
| 53 | Lumberton | 18,694 | -0.6% |
| 54 | Mebane | 18,408 | 3.0% |
| 55 | Lenoir | 18,193 | -0.2% |
| 56 | Boone | 18,036 | -0.2% |
| 57 | Pinehurst | 18,019 | 2.3% |
| 58 | Mount Holly | 17,966 | 1.2% |
| 59 | Hope Mills | 17,786 | 0.3% |
| 60 | Morganton | 17,518 | 0.3% |
| 61 | Graham | 17,273 | 0.6% |
| 62 | Havelock | 17,052 | 0.3% |
| 63 | Albemarle | 16,628 | 1.1% |
| 64 | Stallings | 16,481 | 1.7% |
| 65 | Southern Pines | 15,968 | 2.6% |
| 66 | Eden | 15,319 | -0.4% |
| 67 | Laurinburg | 15,177 | 0.1% |
| 68 | Belmont | 15,136 | 1.1% |
| 69 | Davidson | 15,132 | 0.4% |
| 70 | Roanoke Rapids | 15,128 | -0.7% |
| 71 | Hendersonville | 15,099 | 0.2% |
| 72 | Henderson | 14,954 | -1.0% |
| 73 | Reidsville | 14,524 | -0.3% |
| 74 | Lewisville | 13,602 | 1.4% |
| 75 | Weddington | 13,488 | 1.7% |
| 76 | Newton | 13,187 | 0.5% |
| 77 | Archdale | 11,953 | 0.4% |
| 78 | Smithfield | 11,630 | 3.5% |
| 79 | Spring Lake | 11,619 | -0.1% |
| 80 | Wendell | 11,570 | 15.9% |
| 81 | Kings Mountain | 11,409 | 1.9% |
| 82 | Lincolnton | 11,352 | 2.6% |
| 83 | Elon | 11,350 | 0.2% |
| 84 | Summerfield | 11,119 | 0.3% |
| 85 | Pineville | 10,678 | 0.4% |
| 86 | Winterville | 10,591 | 1.3% |
| 87 | Tarboro | 10,569 | -0.7% |
| 88 | Mount Airy | 10,551 | -0.4% |
| 89 | Waynesville | 10,178 | 0.5% |
| 90 | Rolesville | 10,047 | 5.0% |
| 91 | Hillsborough | 9,716 | 0.2% |
| 92 | Washington | 9,705 | -0.9% |
| 93 | Morehead City | 9,688 | 1.3% |
| 94 | Aberdeen | 9,036 | 5.4% |
| 95 | Rockingham | 9,031 | -1.8% |
| 96 | Gibsonville | 9,013 | 0.4% |
| 97 | Wesley Chapel | 8,883 | 1.7% |
| 98 | Oak Island | 8,878 | 4.4% |
| 99 | Oxford | 8,775 | 1.4% |
| 100 | Butner | 8,487 | 1.5% |
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