| Rank | City | 2010 Population | Growth Rate (Annual) |
|---|---|---|---|
| 1 | Charlotte | 731,424 | 2.5% |
| 2 | Raleigh | 403,892 | 3.4% |
| 3 | Greensboro | 269,666 | 1.7% |
| 4 | Winston-Salem | 229,617 | 1.3% |
| 5 | Durham | 228,330 | 1.9% |
| 6 | Fayetteville | 200,564 | 0.1% |
| 7 | Cary | 135,234 | 3.3% |
| 8 | Wilmington | 106,476 | 1.7% |
| 9 | High Point | 104,371 | 1.9% |
| 10 | Greenville | 84,554 | 3.0% |
| 11 | Asheville | 83,393 | 1.4% |
| 12 | Concord | 79,066 | 3.4% |
| 13 | Gastonia | 71,741 | 0.6% |
| 14 | Jacksonville | 70,145 | 0.6% |
| 15 | Rocky Mount | 57,477 | -0.2% |
| 16 | Chapel Hill | 57,233 | 1.8% |
| 17 | Burlington | 49,963 | 0.8% |
| 18 | Wilson | 49,167 | 0.9% |
| 19 | Huntersville | 46,773 | 6.0% |
| 20 | Kannapolis | 42,625 | 1.3% |
| 21 | Hickory | 40,010 | 0.6% |
| 22 | Apex | 37,476 | 5.8% |
| 23 | Goldsboro | 36,437 | -1.0% |
| 24 | Salisbury | 33,662 | 1.0% |
| 25 | Indian Trail | 33,518 | 9.4% |
| 26 | Monroe | 32,797 | 1.8% |
| 27 | Mooresville | 32,711 | 5.3% |
| 28 | Wake Forest | 30,117 | 8.7% |
| 29 | New Bern | 29,524 | 2.4% |
| 30 | Sanford | 28,094 | 1.8% |
| 31 | Matthews | 27,198 | 1.7% |
| 32 | Thomasville | 26,757 | 0.9% |
| 33 | Garner | 25,745 | 3.2% |
| 34 | Asheboro | 25,012 | 1.2% |
| 35 | Cornelius | 24,866 | 5.8% |
| 36 | Holly Springs | 24,661 | 9.3% |
| 37 | Statesville | 24,532 | 0.4% |
| 38 | Kernersville | 23,123 | 2.1% |
| 39 | Mint Hill | 22,722 | 2.8% |
| 40 | Kinston | 21,677 | -0.9% |
| 41 | Lumberton | 21,542 | 0.2% |
| 42 | Havelock | 20,735 | -0.8% |
| 43 | Shelby | 20,323 | -0.3% |
| 44 | Carrboro | 19,582 | 1.0% |
| 45 | Lexington | 18,931 | -0.5% |
| 46 | Elizabeth City | 18,683 | 0.8% |
| 47 | Clemmons | 18,627 | 1.6% |
| 48 | Morrisville | 18,576 | 12.8% |
| 49 | Lenoir | 18,228 | 0.1% |
| 50 | Fuquay-Varina | 17,937 | 8.1% |
| 51 | Boone | 17,122 | 2.4% |
| 52 | Morganton | 16,918 | -0.3% |
| 53 | Clayton | 16,116 | 6.5% |
| 54 | Laurinburg | 15,962 | -0.0% |
| 55 | Albemarle | 15,903 | -0.1% |
| 56 | Roanoke Rapids | 15,754 | -0.8% |
| 57 | Eden | 15,527 | -0.2% |
| 58 | Henderson | 15,368 | -0.6% |
| 59 | Hope Mills | 15,176 | 2.2% |
| 60 | Reidsville | 14,520 | -0.1% |
| 61 | Graham | 14,153 | 0.7% |
| 62 | Stallings | 13,831 | 6.7% |
| 63 | Mount Holly | 13,656 | 3.5% |
| 64 | Leland | 13,527 | 12.6% |
| 65 | Hendersonville | 13,137 | 1.4% |
| 66 | Pinehurst | 13,124 | 3.0% |
| 67 | Newton | 12,968 | 0.2% |
| 68 | Lewisville | 12,639 | 0.8% |
| 69 | Southern Pines | 12,334 | 1.0% |
| 70 | Spring Lake | 11,964 | -0.4% |
| 71 | Harrisburg | 11,526 | 9.4% |
| 72 | Archdale | 11,415 | 2.3% |
| 73 | Tarboro | 11,415 | 0.2% |
| 74 | Knightdale | 11,401 | 6.1% |
| 75 | Mebane | 11,393 | 4.1% |
| 76 | Smithfield | 10,966 | -0.1% |
| 77 | Davidson | 10,944 | 4.2% |
| 78 | Lincolnton | 10,486 | 0.4% |
| 79 | Mount Airy | 10,388 | -0.5% |
| 80 | Kings Mountain | 10,296 | 0.0% |
| 81 | Summerfield | 10,232 | 4.1% |
| 82 | Belmont | 10,076 | 1.3% |
| 83 | Waynesville | 9,869 | 0.3% |
| 84 | Waxhaw | 9,859 | 12.3% |
| 85 | Washington | 9,744 | 0.0% |
| 86 | Rockingham | 9,558 | – |
| 87 | Weddington | 9,459 | 3.4% |
| 88 | Elon | 9,419 | 3.3% |
| 89 | Winterville | 9,269 | 6.7% |
| 90 | Dunn | 9,263 | -0.0% |
| 91 | Morehead City | 8,661 | 0.9% |
| 92 | Clinton | 8,639 | 0.0% |
| 93 | Oxford | 8,461 | 0.1% |
| 94 | Roxboro | 8,362 | -0.4% |
| 95 | Conover | 8,165 | 1.9% |
| 96 | Siler City | 7,887 | 1.1% |
| 97 | Black Mountain | 7,848 | 0.4% |
| 98 | Marion | 7,838 | 1.3% |
| 99 | Brevard | 7,609 | 1.1% |
| 100 | Butner | 7,591 | 1.6% |
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