| Rank | City | 2009 Population (Est.) | Growth Rate (Annual) |
|---|---|---|---|
| 1 | Charlotte | 687,971 | 2.4% |
| 2 | Raleigh | 393,692 | 3.9% |
| 3 | Greensboro | 251,179 | 1.2% |
| 4 | Winston-Salem | 227,834 | 1.5% |
| 5 | Durham | 223,328 | 2.1% |
| 6 | Fayetteville | 195,234 | -0.3% |
| 7 | Cary | 129,225 | 3.6% |
| 8 | High Point | 102,266 | 2.1% |
| 9 | Wilmington | 100,397 | 1.4% |
| 10 | Greenville | 79,573 | 3.0% |
| 11 | Jacksonville | 79,364 | 2.4% |
| 12 | Asheville | 75,915 | 0.5% |
| 13 | Gastonia | 72,213 | 0.8% |
| 14 | Concord | 66,105 | 2.0% |
| 15 | Rocky Mount | 59,583 | 0.2% |
| 16 | Chapel Hill | 52,636 | 1.2% |
| 17 | Burlington | 50,659 | 1.2% |
| 18 | Wilson | 48,298 | 0.9% |
| 19 | Huntersville | 44,111 | 6.8% |
| 20 | Kannapolis | 42,720 | 1.7% |
| 21 | Hickory | 41,106 | 1.1% |
| 22 | Goldsboro | 38,198 | -0.6% |
| 23 | Apex | 33,191 | 5.7% |
| 24 | Monroe | 32,741 | 2.3% |
| 25 | Salisbury | 30,927 | 0.1% |
| 26 | Sanford | 29,190 | 2.8% |
| 27 | New Bern | 28,584 | 2.6% |
| 28 | Wake Forest | 27,138 | 9.6% |
| 29 | Garner | 27,089 | 4.6% |
| 30 | Matthews | 26,876 | 1.9% |
| 31 | Statesville | 26,396 | 1.4% |
| 32 | Thomasville | 26,371 | 0.9% |
| 33 | Asheboro | 24,480 | 1.2% |
| 34 | Cornelius | 24,470 | 7.1% |
| 35 | Kernersville | 22,804 | 2.4% |
| 36 | Kinston | 22,175 | -0.9% |
| 37 | Mooresville | 21,914 | 1.5% |
| 38 | Havelock | 21,864 | -0.3% |
| 39 | Lumberton | 21,781 | 0.4% |
| 40 | Shelby | 21,340 | 0.3% |
| 41 | Holly Springs | 20,786 | 9.4% |
| 42 | Mint Hill | 20,325 | 2.1% |
| 43 | Lexington | 20,213 | 0.2% |
| 44 | Elizabeth City | 20,181 | 2.0% |
| 45 | Indian Trail | 18,942 | 4.2% |
| 46 | Carrboro | 18,126 | 0.3% |
| 47 | Lenoir | 17,877 | -0.2% |
| 48 | Clemmons | 17,473 | 1.2% |
| 49 | Morganton | 17,020 | -0.3% |
| 50 | Fuquay-Varina | 16,927 | 9.5% |
| 51 | Roanoke Rapids | 16,327 | -0.5% |
| 52 | Henderson | 15,763 | -0.5% |
| 53 | Clayton | 15,636 | 7.8% |
| 54 | Albemarle | 15,505 | -0.4% |
| 55 | Laurinburg | 15,452 | -0.4% |
| 56 | Eden | 15,354 | -0.4% |
| 57 | Reidsville | 14,746 | 0.1% |
| 58 | Graham | 14,492 | 1.1% |
| 59 | Boone | 14,142 | 0.6% |
| 60 | Morrisville | 13,651 | 11.9% |
| 61 | Hope Mills | 13,650 | 1.4% |
| 62 | Newton | 13,457 | 0.7% |
| 63 | Lewisville | 13,003 | 1.3% |
| 64 | Smithfield | 12,877 | 1.9% |
| 65 | Southern Pines | 12,692 | 1.7% |
| 66 | Pinehurst | 12,267 | 2.8% |
| 67 | Hendersonville | 12,114 | 0.7% |
| 68 | Spring Lake | 12,057 | -0.4% |
| 69 | Kings Mountain | 11,074 | 0.9% |
| 70 | Lincolnton | 10,774 | 0.8% |
| 71 | Mount Airy | 10,630 | -0.3% |
| 72 | Mebane | 10,544 | 4.1% |
| 73 | Davidson | 10,290 | 4.5% |
| 74 | Tarboro | 10,150 | -1.2% |
| 75 | Washington | 10,109 | 0.5% |
| 76 | Mount Holly | 10,086 | 0.5% |
| 77 | Dunn | 9,966 | 0.9% |
| 78 | Waynesville | 9,938 | 0.5% |
| 79 | Weddington | 9,853 | 4.8% |
| 80 | Morehead City | 9,508 | 2.4% |
| 81 | Belmont | 9,456 | 0.8% |
| 82 | Archdale | 9,250 | 0.2% |
| 83 | Stallings | 9,115 | 3.0% |
| 84 | Rockingham | 8,849 | -1.0% |
| 85 | Clinton | 8,699 | 0.1% |
| 86 | Roxboro | 8,668 | -0.1% |
| 87 | Siler City | 8,632 | 2.5% |
| 88 | Oxford | 8,623 | 0.3% |
| 89 | Oak Island | 8,241 | 2.7% |
| 90 | Knightdale | 8,159 | 3.3% |
| 91 | Unionville | 7,892 | 5.9% |
| 92 | Black Mountain | 7,860 | 0.5% |
| 93 | Summerfield | 7,674 | 1.4% |
| 94 | Conover | 7,359 | 1.1% |
| 95 | Elon | 7,091 | 0.5% |
| 96 | Forest City | 6,994 | -0.9% |
| 97 | Marion | 6,975 | 0.2% |
| 98 | Trinity | 6,952 | 0.4% |
| 99 | Pineville | 6,951 | 1.8% |
| 100 | Selma | 6,930 | 1.6% |
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