| Rank | City | 2004 Population (Est.) | Growth Rate (Annual) |
|---|---|---|---|
| 1 | Portland | 63,966 | -0.1% |
| 2 | Lewiston | 35,704 | 0.1% |
| 3 | Bangor | 31,741 | 0.3% |
| 4 | South Portland | 23,427 | 0.1% |
| 5 | Auburn | 23,346 | 0.2% |
| 6 | Biddeford | 21,961 | 1.4% |
| 7 | Augusta | 18,613 | 0.1% |
| 8 | Saco | 17,847 | 1.7% |
| 9 | Westbrook | 16,028 | -0.2% |
| 10 | Waterville | 15,704 | 0.2% |
| 11 | Bath | 9,640 | 1.4% |
| 12 | Presque Isle | 9,316 | -0.6% |
| 13 | Brewer | 9,095 | 0.4% |
| 14 | Caribou | 8,194 | -0.5% |
| 15 | Old Town | 7,884 | -0.0% |
| 16 | Rockland | 7,630 | 0.1% |
| 17 | Ellsworth | 6,763 | 1.5% |
| 18 | Belfast | 6,739 | 1.5% |
| 19 | Gardiner | 6,171 | -0.1% |
| 20 | Calais | 3,324 | -1.1% |
| 21 | Hallowell | 2,506 | 0.5% |
| 22 | Eastport | 1,583 | -1.1% |
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