| Rank | City | 2003 Population (Est.) | Growth Rate (Annual) |
|---|---|---|---|
| 1 | Portland | 64,056 | -0.1% |
| 2 | Lewiston | 35,595 | -0.1% |
| 3 | Bangor | 31,641 | 0.3% |
| 4 | Auburn | 23,242 | 0.1% |
| 5 | South Portland | 23,134 | -0.5% |
| 6 | Biddeford | 21,866 | 1.9% |
| 7 | Augusta | 18,680 | 0.3% |
| 8 | Saco | 17,586 | 1.9% |
| 9 | Westbrook | 16,076 | -0.2% |
| 10 | Waterville | 15,680 | 0.2% |
| 11 | Presque Isle | 9,333 | -0.9% |
| 12 | Bath | 9,250 | -0.0% |
| 13 | Brewer | 9,036 | 0.3% |
| 14 | Caribou | 8,207 | -0.6% |
| 15 | Old Town | 7,883 | -0.1% |
| 16 | Rockland | 7,673 | 0.4% |
| 17 | Belfast | 6,675 | 1.8% |
| 18 | Ellsworth | 6,572 | 0.8% |
| 19 | Gardiner | 6,174 | -0.2% |
| 20 | Calais | 3,343 | -1.4% |
| 21 | Hallowell | 2,521 | 1.1% |
| 22 | Eastport | 1,589 | -1.4% |
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