| Rank | City | 2010 Population (Est.) | Growth Rate (Annual) |
|---|---|---|---|
| 1 | Boston | 645,169 | 1.0% |
| 2 | Worcester | 182,882 | 0.7% |
| 3 | Springfield | 155,580 | 0.3% |
| 4 | Cambridge | 108,771 | 0.8% |
| 5 | Lowell | 104,390 | -0.1% |
| 6 | Brockton | 93,527 | -0.1% |
| 7 | New Bedford | 91,053 | -0.3% |
| 8 | Quincy | 91,028 | 0.3% |
| 9 | Fall River | 90,826 | -0.2% |
| 10 | Lynn | 87,517 | -0.2% |
| 11 | Newton | 84,592 | 0.1% |
| 12 | Somerville | 76,491 | -0.1% |
| 13 | Lawrence | 70,579 | -0.2% |
| 14 | Haverhill | 61,578 | 0.5% |
| 15 | Waltham | 60,604 | 0.3% |
| 16 | Malden | 56,146 | -0.0% |
| 17 | Chicopee | 55,915 | 0.2% |
| 18 | Taunton | 55,778 | -0.1% |
| 19 | Medford | 55,578 | -0.0% |
| 20 | Peabody | 51,718 | 0.7% |
| 21 | Revere | 51,693 | 1.0% |
| 22 | Barnstable Town | 46,274 | -0.4% |
| 23 | Methuen | 44,364 | 0.1% |
| 24 | Attleboro | 43,554 | 0.4% |
| 25 | Pittsfield | 42,424 | -0.8% |
| 26 | Leominster | 42,250 | 0.2% |
| 27 | Fitchburg | 42,161 | 0.9% |
| 28 | Westfield | 42,133 | 0.6% |
| 29 | Salem | 41,361 | 0.2% |
| 30 | Holyoke | 40,400 | 0.1% |
| 31 | Beverly | 39,513 | -0.1% |
| 32 | Woburn | 38,983 | 0.5% |
| 33 | Marlborough | 38,465 | 0.6% |
| 34 | Everett | 38,299 | 0.0% |
| 35 | Chelsea | 37,483 | 0.7% |
| 36 | Watertown | 33,117 | 0.0% |
| 37 | Franklin | 32,065 | 0.9% |
| 38 | Gloucester | 30,530 | 0.1% |
| 39 | Northampton | 28,528 | -0.2% |
| 40 | Agawam | 28,485 | 0.1% |
| 41 | West Springfield | 28,137 | 0.1% |
| 42 | Melrose | 27,091 | -0.0% |
| 43 | Gardner | 20,952 | 0.1% |
| 44 | Newburyport | 17,591 | 0.3% |
| 45 | Easthampton | 16,262 | 0.2% |
| 46 | North Adams | 13,816 | -0.6% |
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