| Rank | City | 2000 Population | Growth Rate (Annual) |
|---|---|---|---|
| 1 | Oklahoma City | 507,579 | 1.3% |
| 2 | Tulsa | 392,850 | 0.7% |
| 3 | Norman | 96,821 | 1.9% |
| 4 | Lawton | 92,559 | 1.3% |
| 5 | Broken Arrow | 80,686 | 3.3% |
| 6 | Edmond | 68,553 | 2.7% |
| 7 | Midwest City | 54,310 | 0.4% |
| 8 | Enid | 46,919 | 0.3% |
| 9 | Moore | 41,266 | 0.3% |
| 10 | Stillwater | 39,259 | 0.7% |
| 11 | Muskogee | 39,176 | 0.2% |
| 12 | Bartlesville | 34,767 | 0.1% |
| 13 | Shawnee | 29,149 | 0.7% |
| 14 | Ponca City | 25,956 | -0.3% |
| 15 | Ardmore | 23,660 | 0.2% |
| 16 | Duncan | 22,501 | 0.1% |
| 17 | Del City | 22,130 | -0.8% |
| 18 | Altus | 21,300 | -0.3% |
| 19 | Yukon | 21,057 | 0.0% |
| 20 | Bethany | 20,297 | 0.1% |
| 21 | Sapulpa | 20,145 | 0.9% |
| 22 | Owasso | 18,920 | 5.0% |
| 23 | McAlester | 17,769 | 0.3% |
| 24 | Sand Springs | 17,566 | 0.8% |
| 25 | El Reno | 16,204 | 0.3% |
| 26 | Ada | 16,071 | 0.0% |
| 27 | Chickasha | 15,911 | 0.3% |
| 28 | Claremore | 15,890 | 1.4% |
| 29 | Tahlequah | 14,598 | 2.8% |
| 30 | Durant | 14,181 | 0.8% |
| 31 | Miami | 13,718 | 0.2% |
| 32 | Bixby | 13,532 | 3.7% |
| 33 | Mustang | 13,237 | 2.4% |
| 34 | Okmulgee | 12,992 | -0.4% |
| 35 | Woodward | 11,807 | -0.6% |
| 36 | Guymon | 10,551 | 3.0% |
| 37 | Elk City | 10,490 | -0.1% |
| 38 | The Village | 10,149 | -0.2% |
| 39 | Guthrie | 9,928 | -0.5% |
| 40 | Weatherford | 9,876 | -0.3% |
| 41 | Warr Acres | 9,726 | 0.3% |
| 42 | Jenks | 9,696 | 2.3% |
| 43 | Choctaw | 9,517 | 1.0% |
| 44 | Pryor Creek | 8,848 | 0.6% |
| 45 | Clinton | 8,834 | -0.5% |
| 46 | Glenpool | 8,421 | 2.0% |
| 47 | Cushing | 8,349 | 1.4% |
| 48 | Sallisaw | 8,060 | 1.2% |
| 49 | Poteau | 8,003 | 0.8% |
| 50 | Wagoner | 7,701 | 1.1% |
| 51 | Blackwell | 7,620 | -0.0% |
| 52 | Coweta | 7,387 | 1.1% |
| 53 | Idabel | 7,037 | -0.1% |
| 54 | Seminole | 6,877 | -0.6% |
| 55 | Anadarko | 6,635 | -0.0% |
| 56 | Pauls Valley | 6,260 | 0.1% |
| 57 | Henryetta | 6,146 | 0.3% |
| 58 | Vinita | 6,123 | 0.3% |
| 59 | Tecumseh | 6,109 | 0.5% |
| 60 | Catoosa | 6,086 | 2.8% |
| 61 | Holdenville | 5,685 | 1.5% |
| 62 | Skiatook | 5,587 | 0.7% |
| 63 | Purcell | 5,579 | 1.4% |
| 64 | Hugo | 5,575 | -0.8% |
| 65 | Newcastle | 5,545 | 2.6% |
| 66 | Noble | 5,277 | 0.8% |
| 67 | Alva | 5,258 | -0.7% |
| 68 | Perry | 5,241 | -0.0% |
| 69 | Grove | 5,224 | 2.6% |
| 70 | Blanchard | 4,887 | 6.8% |
| 71 | Sulphur | 4,780 | -0.4% |
| 72 | Harrah | 4,771 | 0.6% |
| 73 | Watonga | 4,681 | 3.1% |
| 74 | Frederick | 4,613 | -1.4% |
| 75 | Lone Grove | 4,612 | 1.6% |
| 76 | Marlow | 4,579 | -0.1% |
| 77 | Tuttle | 4,315 | 1.6% |
| 78 | Bristow | 4,278 | -0.0% |
| 79 | Broken Bow | 4,236 | -0.3% |
| 80 | Kingfisher | 4,221 | 0.1% |
| 81 | Sayre | 4,169 | 3.6% |
| 82 | Collinsville | 4,153 | 1.0% |
| 83 | Fort Gibson | 4,057 | 1.8% |
| 84 | Nichols Hills | 4,055 | 0.1% |
| 85 | Pocola | 4,007 | 0.9% |
| 86 | Nowata | 3,993 | 0.2% |
| 87 | Hobart | 3,993 | -0.7% |
| 88 | Hominy | 3,796 | 1.4% |
| 89 | Spencer | 3,750 | -0.5% |
| 90 | Piedmont | 3,685 | 3.7% |
| 91 | Slaughterville | 3,644 | 3.9% |
| 92 | Pawhuska | 3,628 | -0.8% |
| 93 | McLoud | 3,561 | 2.5% |
| 94 | Wewoka | 3,555 | -1.7% |
| 95 | Checotah | 3,474 | 0.6% |
| 96 | Madill | 3,460 | 1.1% |
| 97 | Cleveland | 3,404 | 0.6% |
| 98 | Stilwell | 3,346 | 0.6% |
| 99 | Dewey | 3,325 | -0.4% |
| 100 | Tonkawa | 3,282 | 0.4% |
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