| Rank | City | 2000 Population | Growth Rate (Annual) |
|---|---|---|---|
| 1 | Baltimore | 648,654 | -1.3% |
| 2 | Frederick | 53,113 | 2.7% |
| 3 | Gaithersburg | 52,861 | 2.9% |
| 4 | Bowie | 52,259 | 3.3% |
| 5 | Rockville | 47,813 | 0.6% |
| 6 | Hagerstown | 36,779 | 0.2% |
| 7 | Annapolis | 35,985 | 1.0% |
| 8 | College Park | 24,708 | 0.4% |
| 9 | Salisbury | 23,349 | 1.2% |
| 10 | Cumberland | 21,645 | -1.4% |
| 11 | Greenbelt | 21,201 | 0.3% |
| 12 | Laurel | 21,169 | 0.9% |
| 13 | Takoma Park | 17,343 | 0.0% |
| 14 | Westminster | 17,053 | 2.8% |
| 15 | Hyattsville | 15,655 | 1.2% |
| 16 | Aberdeen | 13,911 | 0.3% |
| 17 | New Carrollton | 12,598 | 0.5% |
| 18 | Elkton | 11,983 | 3.4% |
| 19 | Easton | 11,852 | 2.1% |
| 20 | Havre de Grace | 11,497 | 2.5% |
| 21 | Cambridge | 11,115 | -0.4% |
| 22 | Bel Air | 9,829 | 0.9% |
| 23 | Mount Rainier | 8,494 | 0.5% |
| 24 | Frostburg | 8,184 | -1.1% |
| 25 | Bladensburg | 7,668 | -0.5% |
| 26 | Ocean City | 7,185 | 3.4% |
| 27 | La Plata | 6,655 | 1.1% |
| 28 | Mount Airy | 6,598 | 5.4% |
| 29 | Cheverly | 6,440 | 0.5% |
| 30 | Riverdale Park | 6,378 | – |
| 31 | Glenarden | 6,326 | 2.2% |
| 32 | District Heights | 6,107 | -0.4% |
| 33 | Thurmont | 5,658 | 5.1% |
| 34 | Walkersville | 5,206 | 2.4% |
| 35 | Poolesville | 5,177 | 3.1% |
| 36 | Hampstead | 5,130 | 6.8% |
| 37 | Taneytown | 5,128 | 3.3% |
| 38 | Brunswick | 4,918 | -0.3% |
| 39 | Seat Pleasant | 4,890 | -0.9% |
| 40 | Chestertown | 4,762 | 1.8% |
| 41 | Sykesville | 4,208 | 6.1% |
| 42 | Capitol Heights | 4,118 | 1.3% |
| 43 | Pocomoke City | 4,109 | 0.4% |
| 44 | Fruitland | 3,782 | 0.7% |
| 45 | Perryville | 3,679 | 4.2% |
| 46 | Berlin | 3,593 | 2.9% |
| 47 | Indian Head | 3,426 | -0.9% |
| 48 | Manchester | 3,270 | 1.0% |
| 49 | Chesapeake Beach | 3,179 | 3.0% |
| 50 | Denton | 3,086 | -1.4% |
| 51 | Berwyn Heights | 2,957 | 0.0% |
| 52 | Brentwood | 2,846 | -0.1% |
| 53 | Boonsboro | 2,820 | 1.1% |
| 54 | North East | 2,776 | 4.2% |
| 55 | Chevy Chase | 2,733 | -0.7% |
| 56 | Crisfield | 2,730 | -1.9% |
| 57 | Middletown | 2,674 | 3.9% |
| 58 | Federalsburg | 2,613 | 1.1% |
| 59 | Forest Heights | 2,587 | -1.0% |
| 60 | Snow Hill | 2,439 | 1.4% |
| 61 | Princess Anne | 2,334 | 2.2% |
| 62 | University Park | 2,320 | 0.4% |
| 63 | Emmitsburg | 2,245 | 1.7% |
| 64 | Mountain Lake Park | 2,242 | 0.9% |
| 65 | Smithsburg | 2,192 | 5.3% |
| 66 | Oakland | 2,161 | 1.2% |
| 67 | Westernport | 2,099 | -2.3% |
| 68 | Chevy Chase Village | 2,049 | -0.0% |
| 69 | Centreville | 1,985 | -0.8% |
| 70 | Leonardtown | 1,901 | 1.2% |
| 71 | Delmar | 1,890 | 1.8% |
| 72 | Hurlock | 1,867 | 1.0% |
| 73 | Williamsport | 1,864 | -3.2% |
| 74 | Kensington | 1,848 | 0.6% |
| 75 | North Beach | 1,760 | 3.8% |
| 76 | Rising Sun | 1,754 | 2.9% |
| 77 | Hancock | 1,743 | -1.1% |
| 78 | Greensboro | 1,637 | 1.1% |
| 79 | Landover Hills | 1,535 | 0.5% |
| 80 | Fairmount Heights | 1,510 | 1.9% |
| 81 | Myersville | 1,406 | 10.4% |
| 82 | Rock Hall | 1,400 | -1.2% |
| 83 | Ridgely | 1,369 | 3.1% |
| 84 | Edmonston | 1,339 | 3.7% |
| 85 | New Windsor | 1,303 | 5.4% |
| 86 | Colmar Manor | 1,259 | 0.2% |
| 87 | Morningside | 1,255 | -1.0% |
| 88 | Trappe | 1,221 | 2.1% |
| 89 | St. Michaels | 1,206 | -0.9% |
| 90 | Lonaconing | 1,202 | -1.4% |
| 91 | Pittsville | 1,184 | 5.7% |
| 92 | Cottage City | 1,137 | -1.1% |
| 93 | Somerset | 1,127 | 0.6% |
| 94 | Charlestown | 1,031 | 4.1% |
| 95 | Union Bridge | 1,005 | 0.5% |
| 96 | Funkstown | 981 | -1.3% |
| 97 | Willards | 942 | 3.4% |
| 98 | Garrett Park | 920 | 0.4% |
| 99 | Martin's Additions | 877 | 0.4% |
| 100 | Chevy Chase View | 866 | 0.3% |
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