| Rank | City | 2010 Population (Est.) | Growth Rate (Annual) | 
|---|---|---|---|
| 1 | New Orleans | 354,850 | -3.4% | 
| 2 | Baton Rouge | 225,388 | -0.1% | 
| 3 | Shreveport | 199,244 | -0.1% | 
| 4 | Lafayette | 114,915 | 0.3% | 
| 5 | Lake Charles | 71,542 | -0.0% | 
| 6 | Kenner | 67,842 | -0.4% | 
| 7 | Bossier City | 63,258 | 1.3% | 
| 8 | Monroe | 51,640 | -0.3% | 
| 9 | Alexandria | 48,849 | 0.5% | 
| 10 | New Iberia | 32,875 | 0.1% | 
| 11 | Houma | 32,584 | -0.1% | 
| 12 | Slidell | 27,477 | 0.7% | 
| 13 | Central | 26,446 | -0.1% | 
| 14 | Opelousas | 23,141 | 0.2% | 
| 15 | Ruston | 21,256 | 0.3% | 
| 16 | Hammond | 20,049 | 1.4% | 
| 17 | Sulphur | 19,635 | -0.5% | 
| 18 | Natchitoches | 17,637 | -0.2% | 
| 19 | Gretna | 16,783 | -0.5% | 
| 20 | Zachary | 15,177 | 3.3% | 
| 21 | Pineville | 14,892 | 0.8% | 
| 22 | Thibodaux | 14,428 | 0.0% | 
| 23 | Crowley | 13,878 | -0.4% | 
| 24 | Baker | 13,440 | -0.3% | 
| 25 | West Monroe | 12,910 | -0.3% | 
| 26 | Minden | 12,797 | -0.4% | 
| 27 | Bogalusa | 12,601 | -0.6% | 
| 28 | Mandeville | 12,557 | 1.9% | 
| 29 | Abbeville | 12,229 | 0.3% | 
| 30 | Bastrop | 11,627 | -1.2% | 
| 31 | Eunice | 11,451 | -0.0% | 
| 32 | Morgan City | 11,434 | -1.1% | 
| 33 | Jennings | 10,428 | -0.5% | 
| 34 | Denham Springs | 10,375 | 0.9% | 
| 35 | Westwego | 10,232 | -0.5% | 
| 36 | DeRidder | 10,163 | 0.5% | 
| 37 | Gonzales | 9,553 | 1.7% | 
| 38 | Harahan | 9,433 | -0.5% | 
| 39 | Covington | 9,224 | 0.8% | 
| 40 | Scott | 9,174 | 1.5% | 
| 41 | Rayne | 8,582 | 0.1% | 
| 42 | Oakdale | 8,103 | -0.0% | 
| 43 | Ville Platte | 8,081 | -0.6% | 
| 44 | Breaux Bridge | 8,033 | 0.6% | 
| 45 | Broussard | 7,983 | 2.9% | 
| 46 | Donaldsonville | 7,653 | 0.0% | 
| 47 | Franklin | 7,577 | -1.0% | 
| 48 | Tallulah | 7,352 | -2.5% | 
| 49 | Youngsville | 7,250 | 6.7% | 
| 50 | St. Martinville | 6,977 | -0.0% | 
| 51 | Carencro | 6,804 | 1.1% | 
| 52 | Plaquemine | 6,658 | -0.6% | 
| 53 | Ponchatoula | 6,375 | 2.1% | 
| 54 | Walker | 6,364 | 3.1% | 
| 55 | Leesville | 5,873 | -1.5% | 
| 56 | Jeanerette | 5,845 | -0.4% | 
| 57 | Marksville | 5,662 | 0.1% | 
| 58 | St. Gabriel | 5,546 | -0.1% | 
| 59 | Mansfield | 5,339 | -0.4% | 
| 60 | Patterson | 5,246 | 0.3% | 
| 61 | Springhill | 5,077 | -0.7% | 
| 62 | Winnfield | 5,037 | -1.4% | 
| 63 | Kaplan | 4,997 | -0.5% | 
| 64 | Port Allen | 4,907 | -0.8% | 
| 65 | Grambling | 4,905 | 0.1% | 
| 66 | Winnsboro | 4,771 | -1.2% | 
| 67 | New Roads | 4,708 | -0.6% | 
| 68 | Church Point | 4,655 | -0.2% | 
| 69 | Westlake | 4,594 | -0.2% | 
| 70 | Bunkie | 4,447 | -0.5% | 
| 71 | Amite City | 4,344 | 0.6% | 
| 72 | Berwick | 4,262 | -0.4% | 
| 73 | Lake Providence | 4,191 | -2.1% | 
| 74 | Vidalia | 4,095 | -1.1% | 
| 75 | Jackson | 4,008 | -0.3% | 
| 76 | Rayville | 3,994 | -0.6% | 
| 77 | Addis | 3,916 | 3.1% | 
| 78 | Vivian | 3,875 | -0.4% | 
| 79 | Ball | 3,759 | 0.2% | 
| 80 | Franklinton | 3,746 | 0.3% | 
| 81 | Jonesboro | 3,662 | -0.7% | 
| 82 | Farmerville | 3,581 | -0.6% | 
| 83 | Ferriday | 3,532 | -0.6% | 
| 84 | Lutcher | 3,422 | -0.9% | 
| 85 | Mamou | 3,376 | -0.6% | 
| 86 | Vinton | 3,368 | 0.1% | 
| 87 | Homer | 3,327 | -1.4% | 
| 88 | DeQuincy | 3,292 | -0.3% | 
| 89 | Welsh | 3,259 | -0.4% | 
| 90 | Gramercy | 3,234 | 0.7% | 
| 91 | Haughton | 3,014 | 0.2% | 
| 92 | Delhi | 2,933 | -0.9% | 
| 93 | Lake Arthur | 2,860 | -0.5% | 
| 94 | Jena | 2,847 | -0.5% | 
| 95 | Benton | 2,816 | 2.8% | 
| 96 | Greenwood | 2,764 | 1.3% | 
| 97 | Arcadia | 2,714 | -1.2% | 
| 98 | Many | 2,705 | -0.7% | 
| 99 | Lockport | 2,691 | 0.3% | 
| 100 | Blanchard | 2,671 | 2.1% | 
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