Rank	City	2010 Population (Est.)	Growth Rate (Annual)
1	Wilmington	73,069	0.1%
2	Dover	36,560	1.4%
3	Newark	30,371	0.4%
4	Middletown	12,726	8.1%
5	Smyrna	8,917	4.8%
6	Milford	8,592	2.3%
7	Seaford	7,329	0.9%
8	Elsmere	5,721	-0.2%
9	Georgetown	5,252	1.0%
10	New Castle	5,033	0.1%
11	Laurel	4,047	0.9%
12	Harrington	3,535	1.2%
13	Lewes	3,187	1.0%
14	Millsboro	2,793	1.3%
15	Camden	2,582	2.3%
16	Selbyville	1,911	1.2%
17	Milton	1,863	0.9%
18	Bridgeville	1,703	1.1%
19	Rehoboth Beach	1,609	0.8%
20	Delmar	1,579	1.0%
21	Delaware City	1,532	0.5%
22	Clayton	1,497	1.5%
23	Wyoming	1,435	2.3%
24	Bellefonte	1,302	0.4%
25	Blades	1,193	0.9%
26	Ocean View	1,162	1.2%
27	Newport	1,136	-0.1%
28	Bethany Beach	978	0.9%
29	Greenwood	921	1.0%
30	Felton	909	1.3%
31	Frederica	761	1.5%
32	Dagsboro	588	1.4%
33	South Bethany	533	0.9%
34	Cheswold	518	1.5%
35	Arden	489	0.3%
36	Houston	486	1.4%
37	Townsend	382	1.2%
38	Fenwick Island	371	0.9%
39	Ellendale	367	1.0%
40	Bowers	350	1.5%
41	Odessa	339	1.9%
42	Dewey Beach	322	0.8%
43	Ardentown	310	0.3%
44	Millville	287	1.3%
45	Ardencroft	277	0.4%
46	Kenton	271	1.5%
47	Leipsic	231	1.4%
48	Bethel	205	1.2%
49	Viola	175	1.3%
50	Henlopen Acres	144	0.9%
51	Hartly	89	1.5%
52	Farmington	86	1.5%